6/17/2023 0 Comments Blue iris color![]() However, this phenotype is mainly influenced by genetic factors acting together as a quantitative trait, giving rise to a range of colors from blue to dark brown ( Brues, 1975) generated by complex genetic interactions ( Kanetsky et al., 2002). Eye color is subjected to certain changes along the lifetime ( Sun et al., 2014). This phenotypic trait is polygenic, and its genetic background is variable across different populations. Iris color is a conspicuous phenotypic trait in humans, and its variation is one of the most relevant manifestations of the physical aspect among individuals. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color. The differences we found might respond to the admixed ethnic composition of Argentina therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms ( p < 0,01). We found a remarkable association of HERC2 rs12913832 GG with blue color ( p < 0.01) but the other markers did not show any association with iris color. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429 p=0.004). We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. ![]() The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. ![]()
0 Comments
Leave a Reply. |